Polyunsaturated fat is associated with subclinical inflammation in women with overweight

Abstract

ntroduction: The inflammation process is considered as a central factor with in the aspects that atherosclerosis. Several factors can affect the vascular inflammatory disease, such as dietary and metabolic patterns. Objective: to verify if there is an association between subclinical inflammation and dietary and metabolic factors in women with overweight. Methods: 66 women with overweight (BMI = 29±4,3kg/m2), sedentary with the age of 24±4.1 years. Lipid profile, insulin and C-reactive protein (CRP) were dosed after fasting. The nutrition survey was made through the 24-hour recall. Subclinical inflammation defined by levels of CRP>3,0mg/L. It was utilized t-tests for independent samples, Spearman’ rho, multivariate logistic regression, as significance level p<0,05. Results: Women with vascular inflammation present higher values of blood glucose levels85±8,1vs 83±7,9mg/dL (p=0,02) and BMI of32±5,6 vs 28±3,2kg/m2 (p=0,02), reduced intakeofpolyunsaturatedfats6±5,2 vs 10±8,1% (p=0,03) andfibers13±5,0 vs 20±13,8g/day (p˂0,01). After the analysis of logistic regression, remained as independent decisive factors: the BMI (OR=1,2, IC95% 1,1-1,5) and the total intake of polyunsaturated fat (OR=0,8 IC95% 0,7-0,8). Conclusion: In women with overweight, the total polyunsaturated fats in take is a protective factor, while increasing BMI is an independent predictor factor for the development of the subclinical inflammatory condition.