Please use this identifier to cite or link to this item: https://repositorio.bahiana.edu.br:8443/jspui/handle/bahiana/2995
Title: Prognostic ability of quick-SOFA across different age groups of patients with suspected infection outside the intensive care unit: A cohort study
Other Titles: Journal of Critical Care
Authors: Teixeira, Mauricio Brito
Ramos, João Gabriel Rosa
Passos, Rogério da Hora
Gobatto, Andre Luiz Nunes
Coutinho, Rafael Viana dos Santos
Caldas, Juliana Ribeiro
Guarda, Suzete Farias da
Ribeiro, Michel Pordeus
Batista, Paulo Benigno Pena
Keywords: Sepsis; Older patients; Screening; Diagnosis; Emergency department
Issue Date: 2018
Abstract: Objectives: Sepsis identification in older patients is challenging. We evaluated the performance of qSOFA across different age groups of patients with suspected infection outside the intensive care unit (ICU). Methods: Retrospective cohort in a tertiary hospital in Brazil, from January 2016 to December 2016. Outcomes were hospital mortality, ICU admission and bacteremia. Performance of qSOFA was compared over three age groups: (1) reference: ≤65 years, (2) old: 65 to 79 years and (3) very old: ≥80 years. Results: There were 420 patients in the study, of which 259 (61.7%) were ≤65 years, 80 (19%) were 65 to 79 years and 81 (19.3%) were ≥80 years. Old and very old patients had higher qSOFA scores and lower SIRS scores. Overall, qSOFA ≥2 was associated to hospital mortality [OR (95% CI) = 5.8 (3.3–10.4), p b 0.001], ICU admission [OR (95%CI) = 2.7 (1.6–4.6), p b 0.001] and bacteremia [OR (95% CI) = 3.1 (1.7–5.8), p b 0.001]. Those associations were stronger in old and very old patients. qSOFA and SIRS demonstrated overall AUROCs for hospital mortality of 0.72 and 0.50, respectively. Conclusion: qSOFA demonstrated good overall accuracy and was more strongly associated to outcomes in old and very old patients, when compared to younger patients.
URI: http://www7.bahiana.edu.br//jspui/handle/bahiana/2995
ISSN: 0883-9441
Appears in Collections:Artigos Completos Publicados em Periódicos

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