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Use este identificador para citar ou linkar para este item: https://repositorio.bahiana.edu.br:8443/jspui/handle/bahiana/2499
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dc.contributor.authorRibeiro, Juliana Caldas-
dc.date.accessioned2018-09-19T18:39:53Z-
dc.date.available2018-09-19T18:39:53Z-
dc.date.issued2018-
dc.identifier.urihttp://www7.bahiana.edu.br//jspui/handle/bahiana/2499-
dc.descriptionWe aimed to assess cerebral autoregulation (CA) and neurovascular coupling (NVC) in stroke patients of differing severity comparing responses to healthy controls and explore the association between CA and NVC with functional outcome. Patients admitted with middle cerebral artery (MCA) stroke and healthy controls were recruited. Stroke severity was defined by the National Institutes of Health Stroke Scale (NIHSS) scores: 4 mild, 5–15 moderate and 16 severe. Transcranial Doppler ultrasound and Finometer recorded MCA cerebral blood flow velocity (CBFv) and blood pressure, respectively, over 5 min baseline and 1 min passive movement of the elbow to calculate the autoregulation index (ARI) and CBFv amplitude responses to movement. All participants were followed up for three months. A total of 87 participants enrolled in the study, including 15 mild, 27 moderate and 13 severe stroke patients, and 32 control subjects. ARI was lower in the affected hemisphere (AH) of moderate and severe stroke groups. Decreased NVC was seen bilaterally in all stroke groups. CA and NVC correlated with stroke severity and functional outcome. CBFv regulation is significantly impaired in acute stroke, and further compromised with increasing stroke severity. Preserved CA and NVC in the acute period were associated with improved three-month functional outcome.pt_BR
dc.description.localpubSalvador/BApt_BR
dc.language.isoenpt_BR
dc.subjectStroke. Severity. Cerebral autoregulation. Neurovascular coupling. Outcome.pt_BR
dc.titleImpaired cerebral autoregulation and neurovascular coupling in middle cerebral artery stroke: Influence of severity?pt_BR
dc.title.alternativeJournal of Cerebral Blood Flow & Metabolism 0(00) 1–9pt_BR
dc.typeProdução técnica: Outra produção técnicapt_BR
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