OLIVEIRA, Márcia Santos deFERRAZ, Sofia Borba de ToledoBARBOSA, Emanuelle Lacerda PintoSILVA JÚNIOR, Hercílio Barbosa daGOULARDINS, Juliana Barbosa2026-03-312026-03-3120252965-3738https://repositorio.bahiana.edu.br/handle/123456789/10207ABSTRACT | BACKGROUND: Transcranial direct current stimulation (tDCS) has shown promise as an adjunctive therapy for neurological and developmental conditions, including autism spectrum disorder (ASD). OBJECTIVE: To describe the preliminary effects of a tDCS protocol combined with traditional speech therapy in two children with ASD. METHODS: This case series involved two male children, aged 4-5 years, diagnosed with ASD. A total of 30 tDCS sessions (1mA, 30 minutes each) were delivered over 10 weeks (CP5–Fp2 montage), combined with language-focused speech therapy. Parents completed the Social Responsiveness Scale (SRS-2) before and after the intervention. RESULTS: Quantitative improvements were observed in social cognition, communication, and motivation, alongside reductions in restrictive behaviors. Qualitative gains included enhanced verbal intention, vocabulary, sentence construction, and emotional regulation. CONCLUSION: These findings support the feasibility and potential therapeutic benefit of combining tDCS with speech therapy in young children with ASD, warranting further investigation in controlled trials.enAutism Spectrum DisorderTranscranial Direct Current StimulationSpeech TherapyNeuromodulationCase SeriesEffects of transcranial direct current stimulation combined with speech therapy in two children with autism spectrum disorder: a clinical case seriesArticlehttps://doi.org/10.17267/2965-3738bis.2025.e64229Tecnologias em Saúde